跳到内容
Epithelial-mesenchymal interactions in the developing lung.
关闭预览资料

Epithelial-mesenchymal interactions in the developing lung.

著者: JM Shannon 附属: Division of Pulmonary Biology, Department of Pediatrics, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio 45229-3039, USA. john.shannon@chmcc.org; BA Hyatt
版本/格式: 文章 文章 : 英语
资源:Annual review of physiology, 2004; 66: 625-45
  同行评审
其它数据库: WorldCatWorldCatExpanded Academic ASAP
提要:
Classical experiments in embryology have shown that normal growth, morphogenetic patterning, and cellular differentiation in the developing lung depend on interactive signaling between the endodermal epithelium and mesenchyme derived from splanchnic mesoderm. These interactions are mediated by a myriad of diffusible factors that are precisely regulated in their temporal and spatial expression. In this review we  再读一些...
未连接到Bethel Libraries的网络上。 如果你想访问在线内容和联系服务部门,可能先要得到你们图书馆的认证。 Off-campus WorldCat
取得资料的在线复本... 取得资料的在线复本...

在图书馆查找

正在查找此资料的位置以及馆藏信息... 正在查找此资料的位置以及馆藏信息...

WorldCat

在全球的图书馆查找
全世界的图书馆都拥有这资料

详细书目

文档类型 文章
所有的著者/提供者: JM Shannon 附属: Division of Pulmonary Biology, Department of Pediatrics, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio 45229-3039, USA. john.shannon@chmcc.org; BA Hyatt
ISSN:0066-4278
语言注释: English
专有的标识符 112065437
奖励:

摘要:

Classical experiments in embryology have shown that normal growth, morphogenetic patterning, and cellular differentiation in the developing lung depend on interactive signaling between the endodermal epithelium and mesenchyme derived from splanchnic mesoderm. These interactions are mediated by a myriad of diffusible factors that are precisely regulated in their temporal and spatial expression. In this review we first describe factors regulating formation of the embryonic foregut. We then discuss the experiments demonstrating the importance of tissue interactions in lung patterning and differentiation. Finally, we detail the roles that a few key signaling systems-fibroblast growth factors and their receptors, sonic hedgehog and Gli genes, Wnt genes and beta-catenin, and BMP4-play as mediators of epithelial-mesenchymal interactions in the developing lung.
有关这份资料的检索注释 有关这份资料的检索注释

评论

用户提供的评论

标签

争取是第一个!
确认申请

你可能已经申请过这份资料。如果还是想申请,请选确认。

关闭窗口

请登入WorldCat 

没有张号吗?很容易就可以 建立免费的账号.